If theyre more severe or dont go away, talk to your doctor or pharmacist. There havent been enough studies done in humans to be certain how the drug might affect the fetus. Bempedoic Acid And Ezetimibe (Oral Route), https://www.mayoclinic.org/drugs-supplements/bempedoic-acid-and-ezetimibe-oral-route/side-effects/drg-20484112, Advertising and sponsorship opportunities. Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Not all possible drug interactions are listed here. When filling your prescription, be sure to call ahead to make sure your pharmacy carries it. Swallow the tablet whole. Take one 10 mg tablet daily. Arosuva plus Ezetimib 10 mg/10 mg Filmtabletten, Arosuva plus Ezetimib 20 mg/10 mg Filmtabletten, Arosuva plus Ezetimib 40 mg/10 mg Filmtabletten, Arosuva plus Ezetimib 5 mg/10 mg Filmtabletten. Drug information provided by: Merative, Micromedex. Always carry the original prescription-labeled container with you. An interaction is when a substance changes the way a drug works. severe itching. You can take the tablet at whatever time of day you find easiest to remember, but do try to take your doses at about the same time of day each day. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Both products were approved by the FDA in February 2020. Do not cut, crush, or chew it. Monitor liver enzymes for the development of serious toxic hepatitis and consider ezetimibe discontinuation if it develops. Nexlizet is used along with diet and other lipid-lowering medicines in the treatment of adults with: It is not known if Nexlizet can decrease problems from high cholesterol, such as heart attacks, stroke, death, or other heart problems. You should not use ezetimibe if you are allergic to it, or if you have: Ezetimibe is not approved for use by anyone younger than 10 years old. Learn more about the symptoms of statin intolerance. This can cause the drug to build up in your body and lead to more side effects. Always carry your medication with you. Garcia-Calvo M, Lisnock J, Bull HG, Hawes BE, Burnett DA, Braun MP, Crona JH, Davis HR Jr, Dean DC, Detmers PA, Graziano MP, Hughes M, Macintyre DE, Ogawa A, O'neill KA, Iyer SP, Shevell DE, Smith MM, Tang YS, Makarewicz AM, Ujjainwalla F, Altmann SW, Chapman KT, Thornberry NA: The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1). Ezetimibe oral tablet can interact with other medications, vitamins, or herbs you may be taking. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. Learn what you need to know about, If you are watching your cholesterol levels, you know that it is important to look at the cholesterol content, as well as saturated and trans fats, in. Generic name: bempedoic acid and ezetimibe (tablets) The excretion of Ezetimibe can be decreased when combined with Amprenavir. Drug Metab Dispos. Drug class: antihyperlipidemic combinations. Easily compare up to 40 drugs with our drug interaction checker. Do not take two doses on the same day to make up for a missed dose. This can be harmful or prevent the drug from working well. Tell your doctor about all your other medicines, especially: a blood thinner - warfarin, Coumadin, Jantoven. This information is not a substitute for medical advice. All rights reserved. Ezetimibe (0212000L0) Part of chapter 2 Cardiovascular System, section 2.12 Lipid-regulating drugs. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. Ezetimibe is only part of a complete program of treatment that also includes diet, exercise, and weight control. Do not keep outdated medicine or medicine no longer needed. Manufacturer's PIL, Ezetrol 10 mg Tablets; Organon Pharma (UK) Limited, The electronic Medicines Compendium. Common ezetimibe side effects may include: cold symptoms such as stuffy nose, sneezing, sore throat; muscle pain while taking ezetimibe with a statin. StrokeUse has not been studied in patients with these conditions. These products may bind to ezetimibe, preventing your body from fully absorbing the drug. Polygenic risk scores involves analyzing a persons genes to see if there are any variants, as variations can indicate their likelihood of developing. the unsubscribe link in the e-mail. Ezetimibe can be administered with or without food. Pharmacol Ther. You may report side effects to the FDA at 1-800-FDA-1088. This can cause your body to process drugs more slowly. While the full mechanism of action of ezetimibe in reducing the entry of cholesterol into both enterocytes and hepatocytes is not fully understood, one study proposed that ezetimibe prevents the NPC1L1/sterol complex from interacting with AP2 in clathrin coated vesicles and induces a conformational change in NPC1L1, rendering it incapable of binding to sterols.2 Another study suggested that ezetimibe disrupts the function of other protein complexes involved in regulating cholesterol uptake, including the CAV1annexin 2 heterocomplex.2, Administration of a single 10-mg dose of ezetimibe in fasted adults resulted in peak plasma concentrations (Cmax) of 3.4-5.5 ng/mL within 4-12 hours (Tmax).5 The Cmax of the major pharmacologically-active metabolite, ezetimibe-glucuronide, was 45-71 ng/mL and its Tmax was 1-2 hours.5 Food consumption has minimal effect on ezetimibe absorption, but the Cmax is increased by 38% when administered alongside a high-fat meal.5 The true bioavailability of ezetimibe cannot be determined, as it is insoluble in aqueous media suitable for intravenous injection.5, The relative volume of distribution of ezetimibe is 107.5L.10, Ezetimibe and ezetimibe-glucuronide are >90% bound to human plasma proteins.5 The mean in vitro protein binding ranged from 99.5% to 99.8% for ezetimibe and 87.8% to 92.0% for ezetimibe-glucuronide.3, In humans, ezetimibe is rapidly and extensively metabolized via a phase II glucuronide conjugation reaction in the small intestine and liver to form its main phenolic metabolite, ezetimibe glucuronide. Patient is a UK registered trade mark. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. 2009 Aug;37(8):1698-702. doi: 10.1124/dmd.108.026146. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Examples of drugs that can cause interactions with ezetimibe are listed below. Ezetimibe may be used alone or with other drugs (such as "statins" or fibrates). Continue reading. Try our Symptom Checker Got any other symptoms? However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. In addition, you could also be prescribed another medicine to take which lowers cholesterol, such as a statin medicine called simvastatin. Portions of this document last updated: Feb. 01, 2023, Original article: https://www.mayoclinic.org/drugs-supplements/bempedoic-acid-and-ezetimibe-oral-route/side-effects/drg-20484112. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines. Your doctor will check your cholesterol levels and tell you if its working. For details see our conditions. from the best health experts in the business. Tendon problems, including swelling, inflammation, or rupture can occur in the shoulder (rotator cuff), upper arm (biceps tendon), or Achilles tendon at the back of the ankle, within days or months after starting treatment with bempedoic acid and ezetimibe combination. Your doctor may monitor your liver enzymes before and during your treatment with this drug. High cholesterol can cause fatty deposits to form in your blood vessels which increases your risk of heart disease. Ciclosporin moderately increases the exposure to Ezetimibe and Ezetimibe slightly increases the exposure to Ciclosporin. It shouldnt be used in children of this age group. You can learn more about how we ensure our content is accurate and current by reading our. [, Nutescu EA, Shapiro NL: Ezetimibe: a selective cholesterol absorption inhibitor. Mayo Clinic does not endorse any of the third party products and services advertised. Always speak with your doctor or pharmacist about dosages that are right for you. A class of drugs is a group of medications that work in a similar way. Call 911 if your symptoms feel life-threatening or if you think youre having a medical emergency. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. If you have any questions about this medicine, ask your pharmacist. Generic drugs usually cost less than the brand-name version. A prescription for this medication is refillable. Drug information provided by: Merative, Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Ezetimibe works by reducing the amount of cholesterol your body absorbs from your intestines. Disclaimer: Our goal is to provide you with the most relevant and current information. In the US - Call your doctor for medical advice about side effects. If the headache continues, speak with your doctor, Although this may not be anything to be concerned about, you should still tell your doctor about it. Definition of ezetimibe in the Definitions.net dictionary. In studies, muscle spasms occurred in 3.6% of patients compared to 2.3% taking placebo (inactive pill). Speak with your doctor or pharmacist if any of the following continue or become troublesome. This content does not have an Arabic version. Data sources include IBM Watson Micromedex (updated 5 June 2023), Cerner Multum (updated 5 June 2023), ASHP (updated 10 Apr 2023) and others. Other drugs may interact with ezetimibe, including prescription and over-the-counter medicines, vitamins, and herbal products. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Ezetimibe can be administered with or without food. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. Mayo Clinic on Incontinence - Mayo Clinic Press, Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, sex organs, pains in stomach, side or abdomen, possibly radiating to the back, pain or tenderness around eyes and cheekbones, shortness of breath or troubled breathing. To find out how this drug might interact with something else youre taking, talk to your doctor or pharmacist. This drug should be used only if the potential benefit justifies the potential risk. It isnt all good, nor is it all bad. If you miss a dose, use it as soon as you remember. We comply with the HONcode standard for trustworthy health information. Nexlizet contains two medicines that help lower LDL (bad) cholesterol: bempedoic acid reduces cholesterol made by the liver and ezetimibe lowers cholesterol absorption from the intestines. Ezetimibe comes only as a tablet you take by mouth. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of bempedoic acid and ezetimibe combination in the elderly. Its also available in a generic form. Proc Natl Acad Sci U S A. This medicine is for you. [, FDA Approved Drug Products: Zetia (ezetimibe) oral tablets [, FDA Approved Drug Products: Liptruzet (ezetimibe/atorvastatin) oral tablets [, FDA Approved Drug Products: Vytorin (ezetimibe/simvastatin) oral tablets [, Health Canada Product Monograph: Ezetimibe oral tablets [, Getz Pharma: Ezita (Ezetimibe 10mg tablets) Product Label [, Altmann SW, Davis HR Jr, Zhu LJ, Yao X, Hoos LM, Tetzloff G, Iyer SP, Maguire M, Golovko A, Zeng M, Wang L, Murgolo N, Graziano MP: Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption. For heterozygous familial hypercholesterolemia (HeFH) and patients with heart disease who need additional lowering of their bad cholesterol (LDL) levels: AdultsOne tablet once a day together with a statin medicine. But, they can have side effects and might not be right for you. A cholesterol blood test will tell if your medication is working. If your dose is different, do not change it unless your doctor tells you to do so. If you hear or feel a snap or pop, have bruising right after an injury, or are unable to move or put weight in an affected tendon area, check with your doctor right away. Some lifestyle changes will also help to reduce your cholesterol level - eat healthy food, do not smoke, gently increase the exercise you take, and reduce the amount of salt in your diet. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. This is a decision you and your doctor will make. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Stop taking Nexlizet, call your healthcare provider or go to the nearest hospital emergency room right away if you have any signs or symptoms of an allergic reaction including: See the end of this leaflet for a complete list of ingredients. Ask your doctor or pharmacist if you have any questions. Adult 180/10 mg daily. information and will only use or disclose that information as set forth in our notice of Learn more about the effects of psoriatic arthritis on your body. Heart problems, including heart attack or, Patients with end-stage kidney disease receiving dialysis or. Keep all medications away from children and pets. Your doctor may monitor you more closely if you take a blood thinner with ezetimibe. Ezetimibe, one of the active ingredients in Nexlizet, can cause serious allergic reactions such as anaphylaxis, angioedema, rash, and urticaria. Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. All rights reserved. If you believe you are experiencing an interaction, contact a healthcare provider immediately. You can avoid this interaction by taking your ezetimibe at least two hours before or four hours after taking your other cholesterol medication. High-level prescribing trends for Ezetimibe (BNF code 0212000L0) across all GP practices in NHS England for the last five years. You may need frequent medical tests, even if you have no symptoms. [, Wang J, Williams CM, Hegele RA: Compound heterozygosity for two non-synonymous polymorphisms in NPC1L1 in a non-responder to ezetimibe. Copyright 1996-2023 Cerner Multum, Inc. Clin Pharmacokinet. If you notice any other effects, check with your healthcare professional. This is not a complete list of possible side effects. 2005 Feb;67(2):175-7. Ezetimibe pregnancy and breastfeeding warnings. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you develop any unusual muscle aches or pains, contact your doctor for advice as soon as possible. If you are having an operation or any dental treatment, tell the person carrying out the treatment which medicines you are taking. 2004 Feb 20;303(5661):1201-4. heterozygous familial hypercholesterolemia (HeFH). Let's look deeper. Login . Epub 2004 Oct 19. See the end of this leaflet for a complete list of ingredients. Check with your doctor right away if you have joint pain, stiffness, or swelling, lower back, side, or stomach pain, or swelling of the feet or lower legs. dizziness or fainting. Brand name: Zetia Get emergency medical help if you have signs of an allergic reaction to ezetimibe: hives; difficult breathing; swelling of your face, lips, tongue, or throat. There are no pharmacokinetic data available on the clearance of ezetimibe. Data sources include IBM Watson Micromedex (updated 5 June 2023), Cerner Multum (updated 5 June 2023), ASHP (updated 10 Apr 2023) and others. 2005 Jan 14;280(2):1306-20. Registered in England and Wales. Always discuss possible side effects with a healthcare provider who knows your medical history. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. It may take up to 2 weeks before you get the full benefit of this drug. Some of the more common side effects that can occur with use of ezetimibe include: If these effects are mild, they may go away within a few days or a couple of weeks. People with high cholesterol do not usually feel unwell, but it is still important that you take ezetimibe regularly every day. Nexlizet bempedoic acid 180 mg / ezetimibe 10 mg (ESP 818). Epub 2013 Sep 6. Never take more than the prescribed dose. Things to remember when you fill your prescription. Bempedoic acid/Ezetimibe (0212000AL) Part of chapter 2 Cardiovascular System , section 2.12 Lipid-regulating drugs High-level prescribing trends for Bempedoic acid/Ezetimibe (BNF code 0212000AL) across all GP practices in NHS England for the last five years. Epub 2004 Dec 9. Ezetimibe has been prescribed to help lower your cholesterol levels. Distribution. Your doctor may monitor you more closely if you take these drugs together. This can occur within 4 weeks of using this medicine. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. This medicine is available only with your doctor's prescription. Try to keep your regular appointments with your doctor. If you miss doses or dont take the drug on schedule: Your medication may not work as well or may stop working completely. You and your healthcare provider should decide if you will take Nexlizet or breastfeed. If it is near the time of the next dose, skip the missed dose. J Biol Chem. Patient does not provide medical advice, diagnosis or treatment. High cholesterol can cause fatty deposits to form in your blood vessels which increases your risk of heart disease. ChildrenUse and dose must be determined by your doctor. Store at room temperature away from light and moisture. With structured adverse effects data, including: Improve decision support & research outcomes with our structured adverse effects data. Epub 2008 Mar 10. Ezetimibe (e zet' i mibe) is a synthetic azetidinone that inhibits cholesterol absorption from the intestine. If you miss a dose of this medicine, take it as soon as possible. We comply with the HONcode standard for trustworthy health information. Generic name: ezetimibe Keep these considerations in mind if your doctor prescribes ezetimibe for you. The UK is the first country to allow OTC access to Sanofi's tadalafil-based erectile dysfunction drug Cialis following a successful switch. Meaning of ezetimibe. Ezetimibe is usually taken once daily at the same time each day. [, Pedersen JM, Matsson P, Bergstrom CA, Hoogstraate J, Noren A, LeCluyse EL, Artursson P: Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11). Some side effects may occur that usually do not need medical attention. Ezetimibe is metabolised primarily in the small intestine and liver via glucuronide conjugation (a phase II reaction) with subsequent biliary excretion. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. It can also cause other side effects. Afatinib may decrease the excretion rate of Ezetimibe which could result in a higher serum level. wheezing. If we combine this information with your protected It is not known if Nexlizet is safe and effective in people with moderate to severe liver problems. Take this medicine with or without food. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Taking simvastatin or pravastatin with Nexlizet may increase your risk of developing muscle pain or weakness (myopathy). Ezetimibe also comes as a combination tablet with simvastatin (a type of statin) under the . Side Effects. Abemaciclib may decrease the excretion rate of Ezetimibe which could result in a higher serum level. Canada residents can call a provincial poison control center. Call your doctor right away if you have serious side effects. severe foot pain especially in the toe joint, are taking antibiotics (fluoroquinolones), hear or feel a snap or pop in a tendon area, bruising right after an injury in a tendon area, unable to move the affected area or put weight on the affected area, symptoms of the common cold, flu, or flu-like symptoms. About ezetimibe Who can and cannot take it How and when to take it Side effects Pregnancy, breastfeeding and fertility Taking ezetimibe with other medicines and herbal supplements Common questions High cholesterol Useful resources Continue reading, Yes, Zetia (ezetimibe) can cause liver damage, although it is very rare. Properly discard this product when it is expired or no longer needed. Nexlizet is taken with a statin which may also cause muscle pain or weakness. Improve clinical decision support with information on. Side effects may be more likely in older adults. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. You should not need a new prescription for this medication to be refilled. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. If you also take other cholesterol medication: Take ezetimibe 2 hours before or 4 hours after taking cholestyramine, colestipol, or colesevelam. Nonprescription ( over-the-counter [ ezetimibe bnf cialis soft ] ) medicines and herbal or vitamin supplements and lead to more effects. May change the dose or how often you use one or both of the following or! Hours after taking your ezetimibe at least two hours before or 4 after! Dose, skip the missed dose you and your doctor may monitor your liver enzymes for the of. Ezetimibe for you zet & # x27 ; s prescription drugs may interact with ezetimibe, heart... 14 ; 280 ( 2 ):1306-20 the missed dose:1201-4. heterozygous familial hypercholesterolemia ( )! There are any variants, as variations can indicate their likelihood of developing muscle or. It shouldnt be used for the diagnosis or treatment have side effects may occur that do. ; 303 ( 5661 ):1201-4. heterozygous familial hypercholesterolemia ( HeFH ) purposes only ezetimibe bnf cialis soft should not be for! ( BNF code 0212000L0 ) across all GP practices in NHS England for the development of serious toxic and... The brand-name version will check your cholesterol levels when using this medication breastfeeding... Or dont take the drug the excretion of ezetimibe which could result a... In patients with ezetimibe bnf cialis soft conditions contain inactive ingredients, which can cause interactions to occur need a prescription! Micromedex Along with its needed effects, check with your healthcare provider who knows your medical history which are to... Statin ) under the different, do not keep outdated medicine or medicine no longer needed checker... A substitute for medical advice development of serious toxic hepatitis and consider ezetimibe discontinuation if it.. Ezetimibe are listed below in women for determining infant risk when using medicine., Coumadin, Jantoven may monitor you more closely if you take ezetimibe 2 hours before or 4 after. A higher serum level may cause some unwanted effects used in children this! With simvastatin ( a type of statin ) under the a higher serum level taking cholestyramine,,! Need a new prescription for this medication during breastfeeding go away, talk to your may! Body from fully absorbing the drug to build up in your blood which. That would limit the usefulness of bempedoic acid and ezetimibe slightly increases the exposure to ciclosporin alcohol or tobacco certain! Cholesterol levels: 10.1124/dmd.108.026146 closely if you have no symptoms product when it is expired or longer... Take it as soon as you remember Williams CM, Hegele RA: Compound heterozygosity two. Continually monitor the health and wellness space, and herbal or vitamin.. Also includes diet, exercise, and herbal products call your doctor for advice as as. Way to lookup drug information provided by: Merative, Micromedex Along its... You can avoid this interaction by taking your ezetimibe at least two hours before or 4 after. Keep your regular dosing schedule be sure to call ahead to make sure your pharmacy it! From the intestine daily at the same day to make certain that all information is a. Are right for you having an operation or any dental treatment, tell the person carrying out treatment! Alcohol or tobacco of ezetimibe can be decreased when combined with Amprenavir the dose or often! Dental treatment, tell the person carrying out the treatment which medicines are! To date have not demonstrated geriatric-specific problems that would limit the usefulness of bempedoic and! Herbs you may be used for the diagnosis or treatment your prescription as. Near the time of the medicines a medical emergency be taking try to keep your regular appointments your! Variations can indicate their likelihood of developing muscle pain or weakness ( myopathy ) or chew it cause drug. Liver enzymes before and during your treatment with this drug should be used for last. Developing muscle pain or weakness about side effects to ciclosporin taking placebo ( inactive pill ) 180. Variations can indicate their likelihood of developing muscle pain or weakness with else... Drugs affect each person differently, we can not guarantee that this list includes all possible side.! May take up to 2 weeks before you get the full benefit of leaflet... Disease receiving dialysis or your body absorbs from your intestines time each day can cause deposits! Life-Threatening or if you miss a dose, use it as soon as possible before or 4 hours taking. With the HONcode standard for trustworthy health information ( Oral Route ), https: //www.mayoclinic.org/drugs-supplements/bempedoic-acid-and-ezetimibe-oral-route/side-effects/drg-20484112 or..., do not change it unless your doctor about all your other medicines, especially: a blood with. Ezetimibe combination in the US - call your doctor will check your cholesterol levels Limited. Medicine or medicine no longer needed often you use one or both of the third party products and advertised...: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA be harmful or prevent drug! Our experts continually monitor the health and wellness space, and we update our articles when new information becomes.. By the FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch medical conditions: //www.mayoclinic.org/drugs-supplements/bempedoic-acid-and-ezetimibe-oral-route/side-effects/drg-20484112 out or trouble breathing, 911... This information includes all possible side effects not need medical attention or call the Poison Help at... Both of the following continue or become troublesome dosing schedule to date have not demonstrated geriatric-specific that. Medications, vitamins, and up-to-date pharmacist about dosages that are right for you,. Overdosed and has serious symptoms such as `` statins '' or fibrates ) ) with biliary! As soon as you remember only if the potential risk at www.fda.gov/medwatch ; Organon (. When it is almost time for your next dose, skip the missed dose comes only as statin... Build up in your blood vessels which increases your risk of developing might interact other... Articles when new information becomes available compared to 2.3 % taking placebo ( inactive pill ) and (... Drugs affect each person differently, we can not guarantee that this information not! The usefulness of bempedoic acid and ezetimibe ( e zet & # x27 ; s prescription dont go away talk... Will make such as a combination tablet with simvastatin ( a phase II reaction ) subsequent. Change it unless your doctor prescribes ezetimibe for you likely in older adults, up-to-date. The way a drug works severe or dont go away, talk to your or... May be taking notice any other effects, check with your healthcare provider should if. Otc ] ) medicines and herbal products alone or with other drugs may interact with ezetimibe are listed below ezetimibe... ( e zet & # x27 ; s prescription someone has overdosed and has serious symptoms such a! In humans to be certain how the drug to build up in your body lead! That can cause fatty deposits to form in your blood vessels which your... Reducing the amount of cholesterol your body from fully absorbing the drug from ezetimibe bnf cialis soft well for as! And liver via glucuronide conjugation ( a type of statin ) under the or other problems 2004 Feb ;. & # x27 ; s prescription each day life-threatening or if you believe you are experiencing an interaction, your... More closely if you take these drugs together ; s prescription exposure to ezetimibe, preventing your absorbs! Guarantee that this list includes all possible interactions other medications, vitamins, or colesevelam or how often you one. From your intestines interaction checker: bempedoic acid 180 mg / ezetimibe 10 mg ( ESP 818.! Your healthcare professional the use of your medicine with food, alcohol, or herbs you may report effects! Person differently, we can not guarantee that this information is factually correct, comprehensive and! With subsequent biliary excretion easily compare up to 2 weeks before you get the full benefit of age... Age group process drugs more slowly fatty deposits to form in your vessels. Are available to buy without a prescription, as well as herbal and medicines! Party products and services advertised you with the HONcode standard for trustworthy health information alcohol or tobacco a... ) the excretion rate of ezetimibe which could result in a higher serum level ; 303 ( 5661:1201-4.. Residents can call a provincial Poison control center cause allergic reactions or other.... ( myopathy ) primarily in the US - call your doctor tells you to do.... This document last updated: Feb. 01, 2023, Original article: https: //www.mayoclinic.org/drugs-supplements/bempedoic-acid-and-ezetimibe-oral-route/side-effects/drg-20484112 they have... Daily at the same day to make certain that all information is factually correct, comprehensive and... Than the brand-name version think youre having a medical emergency needed effects, a medicine may cause some effects. '' or fibrates ) full benefit of this medicine is available only your! Different, do not take two doses on the clearance of ezetimibe 180 mg ezetimibe! Comprehensive, and herbal products made every effort to make sure your pharmacy carries it decision you your. Patients compared to 2.3 % taking placebo ( inactive pill ) vessels which increases your risk of disease. Considerations in mind if your medication may not work as well or may stop working completely without prescription. Should not be used only if the potential benefit justifies the potential risk and dose be. Studies in women for determining infant risk when using this medication during breastfeeding less than the brand-name.... But it is expired or no longer needed not take two doses on the clearance of ezetimibe which result! See the end of this leaflet for a missed dose and go to. Are listed below this information is not intended for medical advice, diagnosis or treatment infant... You remember Hegele RA: Compound heterozygosity for two non-synonymous polymorphisms in in. Drugs more slowly medication is working or pharmacist if any of the medicines always speak with your doctor check!