Select a condition to view a list of medication options. Tell your doctor right away if you develop symptoms of liver problems or pancreatitis such as nausea/vomiting that doesn't stop, unusual tiredness, weakness, swelling of the face, stomach/abdominal pain, loss of appetite, dark urine, or yellowing eyes/skin. Do not stop Depakote without first talking to a healthcare provider. Taking this medication during pregnancy can cause birth defects, may lower your child's IQ, and may increase the risk of your child having certain brain/mental disorders (such as autism, attention deficit/hyperactivity disorder). Occasionally, it may also be used to treat bipolar disorder. Lithium, Divalproex sodium and Quitipine are mood stabilizers and are needed for treatment of Bipolar disorder. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. Depakote 250 Tablet is a medicine used to treat epilepsy. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Got a health query? Your doctor may get your levels of serum amylase checked. POLG mutation screening should be performed in accordance Pancreatitis (inflammation of the pancreas) or. Available in two strengths, Depakote ER contains the same active ingredient as Depakote Delayed-Release Tablets but it is designed to slowly deliver the medication over a 24-hour period. It helps reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. Depakote XR 250 Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor if the hair loss bothers you or persists for a longer duration. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Talk with your doctor about the most appropriate treatment choice for you. Do not chew, crush or break it. Tell your doctor or pharmacist if you are taking other products that cause drowsiness including alcohol, marijuana (cannabis), antihistamines (such as cetirizine, diphenhydramine), drugs for sleep or anxiety (such as alprazolam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), and opioid pain relievers (such as codeine, hydrocodone). This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Your doctor may increase your dose gradually every week by 5 to 10 mg per kg of body weight if needed. Extended-release (ER) tablets: The typical starting dose is 10 mg/kg to 15 mg/kg of body weight by mouth once a day. This medicine is available only with your doctor's prescription. However, it is only for a short time and is usually dose related. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Liver problems may occur while you are using this medicine, and some may be serious. Take your next dose at the regular time. Maintain follow up with your psychiatrist. The dose of this medicine will be different for different patients. DEPAKOTE comes in different dosage forms. AdultsAt first, 500 milligrams (mg) once a day for 1 week. Depakote XR 250 Tablet is a medicine used to treat epilepsy. Some men receiving this medicine have become infertile (unable to have children). Common side effects of Divalproex Sodium include: Other side effects of Divalproex Sodium include: Postmarketing side effects of Divalproex Sodium reported include: This document does not contain all possible side effects and others may occur. A very serious allergic reaction to this drug is rare. If you notice any other effects, check with your healthcare professional. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. It is also used in the prevention of migraines. See also Warning section. Do not use divalproex sodium for migraine headache prevention. Adults and children 10 years of age or olderDose is based on body weight and must be determined by your doctor. Depakote XR 250 Tablet may be used alone or in combination with other medicines. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Ask your pharmacist about using those products safely. It helps prevent and control seizures (fits). Do not drive or do anything that requires mental focus until you know how it affects you. Submit the copay card authorized for all commercially insured patients by the patients primary insurance as a secondary transaction to OPUS Health. Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, pancreatitis, certain metabolic disorders (such as urea cycle disorders, Alpers-Huttenlocher syndrome), alcohol abuse, bleeding problems, brain disease (dementia), kidney disease, dehydration, poor nutrition. Depakote ER 250 mg tablet,extended release, Select a condition to view a list of medication options. If this medication is used for seizures, do not stop taking it without consulting your doctor. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Otherwise, call a poison control center right away. Or call me - Dr. Ambrish Dharmadhikari. Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. You should also be aware that the linked site may be governed by its own set of terms and conditions and privacy policy for which AbbVie has no responsibility. Lab and/or medical tests (such as drug levels, liver function, complete blood counts, clotting tests) should be done before you start taking this medication and while you are taking it. Tell your doctor if you are pregnant or plan to become pregnant. being able to get an erection, but not having it last long enough for sex. It is recommended to periodically monitor liver function during the first 6 months of therapy, primarily in those who seem most at risk and those with a prior history of liver disease. Consult your pharmacist or local waste disposal company. Drug information provided by: Merative, Micromedex. Depakote tablets and capsules have a special coating to prevent the entire tablet from breaking down at the same time. This may occur if you have certain intestinal disorders (such as ileostomy, colostomy). Children younger than 2 years who might have these disorders should not use this medication. However, the dose is usually not more than 1000 mg per day. Yes, Depakote XR 250 Tablet can cause damage to the liver. If at any time a patient begins receiving prescription drug coverage under any such federal, state, or government-funded healthcare program, patient will no longer be able to use the Depakote Savings Card and patient must call OPUS Health at 800.364.4767 to stop participation. In the US - Call your doctor for medical advice about side effects. Depakote XR 250 Tablet works to restore the normal balance of nerve activity in your brain. Tell your doctor right away if you have sudden and severe stomach pain, chills, constipation, nausea, vomiting, fever, or lightheadedness. Laboratory tests should be performed before you start treatment and periodically during treatment, especially within the first 6 months, to monitor this side effect. Properly discard this product when it is expired or no longer needed. Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you. Swallow the tablet whole. Depakote XR 250 Tablet is safe to use in patients with kidney disease. The dose of Depakote XR 250 Tablet should be reduced gradually and eventually can be stopped under the supervision of a doctor or specialist. About Medicine Prescription only medicine Healthcare Professionals (SmPC) Patient Leaflet (PIL) Risk Materials The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. Depakote XR 250 Tablet may cause excessive drowsiness with alcohol. No dose adjustment of Depakote XR 250 Tablet is recommended. Your doctor may increase your dose as needed. Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. This means that Depakote ER only has to be taken once a day. In the US - Call your doctor for medical advice about side effects. I am 30 yr old ,suffering from epilepsy since I was 17, I take DEPAKOTE xr500mg, can I stop medicine completely, I always remain in stress and angry, I sleep late in the night ,how I deal with epilepsy,I am tired of taking medicine, not likely; talk to ur treating doctor about it, Tab. Epilepsy, Migraine are some of its major therapeutic uses. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Yes, Depakote XR 250 Tablet may cause weight gain. Avoid alcoholic beverages. If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Tell your doctor if you are pregnant or plan to become pregnant. If you become pregnant, talk to your doctor right away about the risks and benefits of this medication. Avoid driving or other work that requires mental focus until you know how it affects you. Depakote tablets and capsules are used to treat seizures in people with epilepsy who are at least 10 years old. The dosage is based on your age, weight, medical condition, response to treatment, and other medications you may be taking. What were the side-effects while using Depakote XR 250 Tablet? Depakote Delayed-Release Tablets are delayed-release, which means they have a special coating that prevents the drug from dissolving too early in the digestive tract. 2023 Tata 1mg. We shall seat and discuss your history and decide medications. Read and follow the instructions carefully. You may take it with food if stomach upset occurs. It needs to be taken regularly to work effectively. This medicine is an anticonvulsant that works in the brain tissue to stop seizures. See also Warning section. Avoid alcohol consumption while you are on treatment with Depakote XR 250 Tablet. ChildrenUse and dose must be determined by your doctor. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: fever, swollen lymph nodes, rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Drowsiness, dizziness, unsteadiness can increase the risk of falling. Available in three strengths, Depakote Delayed-Release Tablets must be taken twice a day, as prescribed by your doctor. This is called a ghost tablet, and may contain a trace, if any, amount of medicine. Divalproex sodium is also used to treat the manic phase of bipolar disorder (manic-depressive illness) and helps prevent migraine headaches. being able to get an erection sometimes, but not every time you want to have sex. Stay with the person until professional help arrives. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. However, safety and efficacy have not been established for other indications in children, and to treat seizures in children younger than 10 years of age. All rights reserved. Talk to your pharmacist for more details. Diarrhea, dizziness, drowsiness, hair loss, blurred/double vision, change in menstrual periods, ringing in the ears, shakiness (tremor), unsteadiness, weight changes may occur. If you are taking divalproex sodium only to prevent migraine headaches, this medication must not be used during pregnancy. Symptoms of ED include. Check with your doctor before taking any of the above while you are using this medicine. Do not take Depakote, Depakote ER, and Depakote Sprinkles if you are allergic to divalproex sodium or any ingredients contained in this drug. If you are taking divalproex sodium only to prevent migraine headaches, this medication must not be used during pregnancy. All products displayed on Tata 1mg are procured from verified and licensed pharmacies. Things to remember when you fill your prescription. This is not health insurance. The following information includes only the average doses of this medicine. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Immediately consult your doctor in case you experience these symptoms. Children younger than 6 years may be at greater risk for liver problems and pancreatitis. Keep all medications away from children and pets. Due to an increased risk for liver problems, people with certain inherited metabolic disorders (such as Alpers-Huttenlocher syndrome) should not use this medication. This medication is used to treat seizure disorders, certain psychiatric conditions (manic phase of bipolar disorder ), and to prevent migraine headaches. Do not store in the bathroom. Care plan members get extra discounts, free shipping, free health screening, premium doctor consultation and more. Inform your doctor if your condition does not improve. Oral solution: 250 mg/5 mL; Brand names: Depakote Delayed-release tablets:125 mg, 250 mg, 500 mg; Delayed-release sprinkle capsules: 125 mg; Depakote ER . Check with your doctor right away if this happens. Talk to your doctor for details. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby. T&C Apply. Take this medicine in the dose and duration as advised by your doctor. It may cause dizziness and sleepiness. Divalproex sodium may cause serious allergic reactions affecting multiple body organs (eg, liver or kidney). Do not split, crush, or chew it. The risk of serious liver problems is increased in children younger than 2 years, especially if they have an inherited metabolic disorder, severe seizure disorder with mental retardation, organic brain disease, or if they take more than one seizure medication. Delayed-release (DR) tablets: The typical starting dose is 250 mg by mouth twice a day. Children younger than 10 years of ageUse and dose must be determined by your doctor. May make these conditions worse. For informational purposes only. Do not share this medication with others. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Check with your physician for additional information about side effects. Occasionally, it may also be used to treat bipolar disorder. Your condition may become worse if the drug is suddenly stopped. Patients residing in or receiving treatment in certain states may not be eligible. Using this medicine while you are pregnant (especially during the first 3 months of pregnancy) can harm your unborn baby and cause serious unwanted effects (eg, brain or facial problems, heart or blood vessel problems, arm or leg problems, or intelligence or mental problems). It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain. Dosages expressed as valproic acid equivalents, Indicated for the treatment of manic episodes associated with bipolar disorder, Indicated for prophylaxis of migraine headaches; there is no evidence of use for acute treatment, Conversion to monotherapy: Decrease concomitant anti-epilepsy drug dosage approximately 25% every 2 weeks. It may change the abnormal and excessive activity of the nerve cells in the brain or increase the activity in a region of the brain associated with migraines. The. Suicidal thoughts or behavior. Do not double the dose to catch up. . If you have a shortened intestine (for example, from a colostomy or ileostomy) or an intestinal disorder and diarrhea, you may not have received all your medicine from the tablet. Puneet sir is very good doc., need your expert opinion. Overdose Talk with your doctor Q&A Introduction If you have certain types of seizures, migraine, or mood disorders, your doctor might suggest Depakote or Depakote ER as a treatment option.. Take other medications as directed by your doctor for acute attacks. bloating or swelling of the face, arms, hands, lower legs, or feet, delusions of persecution, mistrust, suspiciousness, or combativeness, false beliefs that cannot be changed by facts, shakiness in the legs, arms, hands, or feet, trembling or shaking of the hands or feet, bruising burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, changes in patterns and rhythms of speech, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, fast, irregular, pounding, or racing heartbeat or pulse, flushing or redness of the skin, especially on the face and neck, large, flat, blue or purplish patches in the skin, multiple swollen and inflamed skin lesions, normal menstrual bleeding occurring earlier, possibly lasting longer than expected, numbness of the feet, hands and around mouth, pains in the stomach, side, or abdomen, possibly radiating to the back, rapid or worm-like movements of the tongue, seeing, hearing, or feeling things that are not there, uncontrolled movements of the arms and legs, unsteadiness, trembling, or other problems with muscle control or coordination, vomiting of blood or material that looks like coffee grounds, blistering, peeling, loosening of the skin, feeling that others are watching you or controlling your behavior, feeling that others can hear your thoughts, feeling, seeing, or hearing things that are not there, increased sensitivity of the skin to sunlight, pain or swelling in the arms or legs without any injury, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, red skin lesions, often with a purple center, redness or other discoloration of the skin, sores, ulcers, or white spots in the mouth or on the lips, tic-like (jerky) movements of the head, face, mouth, and neck, continuing ringing or buzzing or other unexplained noise in the ears, Absent, missed, or irregular menstrual periods, change in taste or bad unusual or unpleasant (after) taste, excess air or gas in the stomach or bowels, feeling of constant movement of self or surroundings, pain or tenderness around the eyes and cheekbones, rash with flat lesions or small raised lesions on the skin, redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid, redness, swelling, or soreness of the tongue, thick, white vaginal discharge with no odor or with a mild odor, discoloration of the fingernails or toenails, increased hair growth, especially on the face, unexpected or excess milk flow from the breasts. Divalproex sodium may cause some people to become dizzy, lightheaded, drowsy, or less alert than they are normally. Divalproex sodium may harm an unborn baby. Ordinarily optimal clinical response is achieved at daily doses below 60 mg/kg/day. In Canada - Call your doctor for medical advice about side effects. Pay with Paytm Wallet and get up to Rs. Take this medication by mouth once daily or as directed by your doctor. Overdose of Depakote XR 250 Tablet may cause headaches, blurred eyesight due to pupils of the eyes becoming smaller, lack of reflexes, confusion and tiredness. Never delay seeking . There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Max. Hepatic failure resulting in fatalities has occurred, Children younger than 2 years are at increased risk for fatal hepatotoxicity, particularly patients on multiple anticonvulsants, as well as those with, Increased risk of valproate-induced acute, If used in children with these conditions, it should be administered with extreme caution as a sole agent, Hepatotoxicity usually occurs during the first 6 months of treatment and may be preceded by, Do not use in women of childbearing age unless the drug is, Children exposed in utero have an increased risk for lower cognitive test scores compared with those exposed in utero to other antiseizure medications, Alternative medications that have a lower risk for adverse birth outcomes should be considered, Patients should not stop taking valproate without talking to a healthcare professional, Women should use effective contraception while taking valproate derivatives, Cases of life-threatening pancreatitis have been reported in children and adults, See "What Are Side Effects Associated with Using Divalproex Sodium?. bipolar I disorder with most recent episode mixed, a type of seizure disorder called tonic-clonic epilepsy, seizures with irregular muscle contractions. Stopping Depakote suddenly can cause serious problems. Some products that may interact with this drug include: certain antidepressants (such as amitriptyline, nortriptyline, phenelzine), certain antibiotics (carbapenems such as imipenem), irinotecan, mefloquine, orlistat, other medications for seizure (such as ethosuximide, lamotrigine, rufinamide, topiramate), warfarin, vorinostat, zidovudine. 2020 AbbVie Inc. North Chicago, IL 60064 US-DPKT-200005 July 2020. Divalproex sodium is used to treat certain types of seizures (epilepsy). Stopping a seizure medicine suddenly in a patient who has epilepsy can cause seizures that will not stop (status epilepticus). "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. The average doses of this medicine depakote xr 250 levitra professional and other medications you may be serious,... 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