Plasma coenzyme Q10 concentrations in breast cancer: prognosis and therapeutic consequences. J Neurol 1998;245:681-5. View abstract. View abstract. View abstract. Bleske BE, Willis RA, Anthony M, et al. View abstract. J Clin Pathol 1993;46:1055-7. The Use of Vitamins and Coenzyme Q10 for the Treatment of Vascular Occlusion Diseases Affecting the Retina. Tsujita, Y., Kunitomo, T., Fujii, M., Furukawa, S., Otsuki, H., Fujino, K., Hamamoto, T., Tabata, T., Matsumura, K., Sasaki, T., Saotome, T., Kawai, H., Matsumoto, T., Maeda, K., Horie, M., and Eguchi, Y. View abstract. Side effects from CoQ10 seem to be rare and mild. J Assist Reprod Genet. Chemica Scripta 1987;27:145-153. View abstract. Heart Lung Circ 2010;19(10):584-591. Yikoski T, Piirainen J, Hanninen O, and et al. Crane FL. Neurology 2001;56:849-55. Coenzyme Q10 is an antioxidant. Kessler A, Sollie S, Challacombe B, Briggs K, Van Hemelrijck M. Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study. Spurney, C. F., Rocha, C. T., Henricson, E., Florence, J., Mayhew, J., Gorni, K., Pasquali, L., Pestronk, A., Martin, G. R., Hu, F., Nie, L., Connolly, A. M., and Escolar, D. M. CINRG pilot trial of coenzyme Q10 in steroid-treated Duchenne muscular dystrophy. Suksomboon N, Poolsup N, Juanak N. Effects of coenzyme Q10 supplementation on metabolic profile in diabetes: a systematic review and meta-analysis. VIII. Weyer G, Babej-Dolle RM, Hadler D, et al. Pineda, M., Montero, R., Aracil, A., O'Callaghan, M. M., Mas, A., Espinos, C., Martinez-Rubio, D., Palau, F., Navas, P., Briones, P., and Artuch, R. Coenzyme Q(10)-responsive ataxia: 2-year-treatment follow-up. View abstract. View abstract. Symptoms such as muscle weakness and fatigue that affect polio survivors. View abstract. Yaghini O, Hoseini N, Ghazavi MR, et al. Kidney failure. 2008;22(12):1403-1408. Anesteziol.Reanimatol. Perhaps, this is the first study that investigates the role of CoQ10 in ED in hypertensive patients. 2011;111(6):404-405. The randomized clinical trial of coenzyme Q10 for the prevention of periprocedural myocardial injury following elective percutaneous coronary intervention. Resuscitation. The impact of coenzyme Q10 on metabolic and cardiovascular disease profiles in diabetic patients: A systematic review and meta-analysis of randomized controlled trials. Damian, M. S., Ellenberg, D., Gildemeister, R., Lauermann, J., Simonis, G., Sauter, W., and Georgi, C. Coenzyme Q10 combined with mild hypothermia after cardiac arrest: a preliminary study. Int J Vitam.Nutr Res 1998;68(2):109-113. Some research shows that taking coenzyme Q10 by itself or along with other supplements might slow mental decline in people with early-stage Parkinson disease. In: Folkers K, Littarru GP and Yamagami T. Biomedical and Clinical Aspects of Coenzyme Q10. Mov Disord. Pediatr.Neurol. View abstract. Int J Sport Nutr. Martucci A, Nucci C. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension. Heart Lung Circ. Balercia, G., Mancini, A., Paggi, F., Tiano, L., Pontecorvi, A., Boscaro, M., Lenzi, A., and Littarru, G. P. Coenzyme Q10 and male infertility. 2017 Feb;23(2):188-189. Am J Clin Nutr 1996;64:622-6. Coenzyme Q10 also seems to have antioxidant activity. Effects of coenzyme Q10 supplementation on inflammation, angiogenesis, and oxidative stress in breast cancer patients: a systematic review and meta-analysis of randomized controlled- trials. Boll.Chim.Farm. Antioxid.Redox.Signal. Diabetes. Impact of ubiquinone (coenzyme Q10) treatment on glycaemic control, insulin requirement and well-being in patients with Type 1 diabetes mellitus. The impact of coenzyme Q10 on systolic function in patients with chronic heart failure. Lou Gehrig's disease (amyotrophic lateral sclerosis or ALS). Hoenjet, K. M., Dagnelie, P. C., Delaere, K. P., Wijckmans, N. E., Zambon, J. V., and Oosterhof, G. O. Lee, B. J., Huang, Y. C., Chen, S. J., and Lin, P. T. Effects of coenzyme Q10 supplementation on inflammatory markers (high-sensitivity C-reactive protein, interleukin-6, and homocysteine) in patients with coronary artery disease. Biofactors 2008;32(1-4):119-128. Neurology 8-24-2004;63(4):727-729. Hershey AD, Powers SW, Vockell AB, et al. Early research suggests that taking coenzyme Q10 by mouth can improve posture and muscle function in people with cerebellar ataxia and low coenzyme Q10 levels. Molec Aspects Med 1994;15:S241-8. Free Radic Biol Med 2004;36:1043-57. Am J Health Syst Pharm 2000;57:1221-7. Heart damage caused by certain cancer drugs (anthracycline cardiotoxicity). official website and that any information you provide is encrypted 5-15-2008;23(7):942-949. Nutrition Research 1997;17(6):941-945. The effect of coenzyme Q10 plus trimetazidine on acute viral myocarditis treatment. View abstract. View abstract. Esteves, A. R., Arduino, D. M., Swerdlow, R. H., Oliveira, C. R., and Cardoso, S. M. Oxidative stress involvement in alpha-synuclein oligomerization in Parkinson's disease cybrids. Bresolin, N., Bet, L., Ferrante, C., Binda, A., Carenzi, A., Moggio, M., Comi, G., and Scarlato, G. Immunological and biochemical studies and pilot therapeutic trial with ubidecarenone in Kearns-Sayre patients. A pilot study. Muta-Takada, K., Terada, T., Yamanishi, H., Ashida, Y., Inomata, S., Nishiyama, T., and Amano, S. Coenzyme Q10 protects against oxidative stress-induced cell death and enhances the synthesis of basement membrane components in dermal and epidermal cells. Explore. View abstract. View abstract. 2008;22(6):832-839. Fumagalli, S., Fattirolli, F., Guarducci, L., Cellai, T., Baldasseroni, S., Tarantini, F., Di, Bari M., Masotti, G., and Marchionni, N. Coenzyme Q10 terclatrate and creatine in chronic heart failure: a randomized, placebo-controlled, double-blind study. Rotig A, Appelkvist EL, Geromel V, et al. Shanmugasundaram ER, Rajeswari G, Baskaran K, et al. View abstract. ED is often a symptom of another health problem or health-related factor. Sun, H. Y. 2010;119(2):82-88. Blood Coagul.Fibrinolysis 2009;20(4):248-251. The prevalence of ED has been shown to be 58.3% in hypertensive patients, considerably high than the general population. View abstract. Ho et al. View abstract. Cardiac performance and coenzyme Q10 in thyroid disorders. J Neuroophthalmol. J Pediatr 2008;153(3):402-407. But it is not clear if these improvements are due to the coenzyme Q10 or an age-related phenomenon. Functions of coenzyme Q10 supplementation on liver enzymes, markers of systemic inflammation, and adipokines in patients affected by nonalcoholic fatty liver disease: a double-blind, placebo-controlled, randomized clinical trial. Schulz, C., Obermuller-Jevic, U. C., Hasselwander, O., Bernhardt, J., and Biesalski, H. K. Comparison of the relative bioavailability of different coenzyme Q10 formulations with a novel solubilizate (Solu Q10). View abstract. Tomasetti, M., Alleva, R., Solenghi, M. D., and Littarru, G. P. Distribution of antioxidants among blood components and lipoproteins: significance of lipids/CoQ10 ratio as a possible marker of increased risk for atherosclerosis. Brain damage that affects muscle movement (cerebellar ataxia). Stojanovic M, Radenkovic M. A meta-analysis of randomized and placebo-controlled clinical trials suggests that coenzyme Q10 at low dose improves glucose and HbA1c levels. Harinstein, M. E., Berliner, J. I., Shah, S. J., Taegtmeyer, H., and Gheorghiade, M. Normalization of ejection fraction and resolution of symptoms in chronic severe heart failure is possible with modern medical therapy: clinical observations in 11 patients. View abstract. Studies on coenzyme Q10 and essential hypertension. Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. These actions lead to the modulation of tone in the penile arteries and the vascular smooth muscles, resulting in erectile dysfunction. View abstract. J Neurol. Meier, T. and Buyse, G. Idebenone: an emerging therapy for Friedreich ataxia. Coenzyme Q10. Berson EL, Rosner B, Sandberg MA, et al. Okamura, T., Sunamori, M., Amano, J., Hirooka, Y., Ozeki, M., Tanaka, A., and Suzuki, A. Rev.Neurol. 2019 Oct;148:104290. View abstract. Med Sci Monit. 1999;4(4):16-19. Parkinson disease. 2016;34(4):254-60. doi: 10.1111/1755-5922.12195. Oda T. Dose-effect relationship and critical dose of coenzyme Q10 on load-induced cardiac dysfunction in pediatric patients with mitral valve prolapse. 2011;131(5):512-517. No Effect of Coenzyme Q10 on Cognitive Function, Psychological Symptoms, and Health-related Outcomes in Schizophrenia and Schizoaffective Disorder: Results of a Randomized, Placebo-Controlled Trial. Mol.Aspects Med 1994;15 Suppl:s149-s154. Tran MT, Mitchell TM, Kennedy DT, Giles JT. What are the side effects? Amyotroph.Lateral.Scler.Other Motor Neuron Disord 2000;1(suppl 4):17-20. 1978;62(6):887-891. 10-15-2001;175(8):447-448. J Am Coll Nutr 2001;20:591-8. View abstract. Coenzyme Q(10) and selenium in statin-associated myopathy treatment. Replacement therapy is effective in familial mitochondrial encephalomyopathy with muscle coenzyme Q10 deficiency. Sunamori, M., Tanaka, H., Maruyama, T., Sultan, I., Sakamoto, T., and Suzuki, A. Levy, G., Kaufmann, P., Buchsbaum, R., Montes, J., Barsdorf, A., Arbing, R., Battista, V., Zhou, X., Mitsumoto, H., Levin, B., and Thompson, J. L. A two-stage design for a phase II clinical trial of coenzyme Q10 in ALS. 1997;42(2):261-264. Coenzyme Q10 is present naturally in the human body. View abstract. Kaufmann, P., Thompson, J. L., Levy, G., Buchsbaum, R., Shefner, J., Krivickas, L. S., Katz, J., Rollins, Y., Barohn, R. J., Jackson, C. E., Tiryaki, E., Lomen-Hoerth, C., Armon, C., Tandan, R., Rudnicki, S. A., Rezania, K., Sufit, R., Pestronk, A., Novella, S. P., Heiman-Patterson, T., Kasarskis, E. J., Pioro, E. P., Montes, J., Arbing, R., Vecchio, D., Barsdorf, A., Mitsumoto, H., and Levin, B. Int J Sports Med 1995;16(7):421-427. Yamagami T, Takagi M, Akagami H, and et al. View abstract. 2012;4:CD004426. First Conference of the International Coenzyme Q10 Association 2002; Tabrizi R, Akbari M, Sharifi N, Lankarani KB, Moosazadeh M, Kolahdooz F, et al. Taking coenzyme Q10 along with medications for high blood pressure might cause your blood pressure to go too low. View abstract. Klin Med (Mosk) 2006;84(5):59-62. Rapid and sensitive analysis of reduced and oxidized coenzyme Q10 in human plasma by ultra performance liquid chromatography-tandem mass spectrometry and application to studies in healthy human subjects. Cochrane Database Syst Rev. Malm C, Svensson M, Ekblom B, et al. Tiredness in people treated with cancer drugs. This information may not fit your specific health circumstances. Coenzyme Q10 therapy. being able to get an erection sometimes, but not every time you want to have sex. Neurology 2001;57:397-404. View abstract. View abstract. View abstract. In conclusion, the supplementation of CoQ10 in hypertensive males with mild ED shows improvement as compared to the control group, which only received the regular antihypertensive medication. Rev Med Interne 1992;13(5):381-383. 1993;71(8 Suppl):S162-S166. Jpn.Heart J 1976;17(1):32-42. [Interaction between warfarin and coenzyme Q10]. Clin Investig. Gastric acidity influences the blood response to a beta-carotene dose in humans. Ubiquinol (reduced coenzyme Q10) as a metabolic resuscitator in post-cardiac arrest: A randomized, double-blind, placebo-controlled trial. Costeff, H., Apter, N., Elpeleg, O. N., Prialnic, M., and Bohles, H. J. Ineffectiveness of oral coenzyme Q10 supplementation in 3- methylglutaconic aciduria, type 3. The use of CoQ10 has not been studied in hypertensive males with ED before, but there are several studies regarding its use in other diseases exploring the same principle of action. Early research shows that taking a specific form of coenzyme Q10 called ubiquinol improves autism symptoms in autism patients aged 3-6 years according to parent assessment. View abstract. View abstract. Highlights in Ubiquinone Research 1990;303-308. Balercia G, Mosca F, Mantero F, et al. View abstract. 2010;12(4):537-577. Biomedical and clinical aspects of coenzyme Q. Amsterdam: Elsevier/North-Holland Biomedical Press 1980;2:139-54. View abstract. Koroshetz WJ. Rev.Neurol. 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Electron transfer mediators and other metabolites and cofactors in the treatment of mitochondrial dysfunction. Murata, T., Ohtsuka, C., and Terayama, Y. Ann Intern Med 2000;132:636-40. 2009;19(5):501-506. Chan A, Reichmann H, Kogel A, et al. Assessment of the effectiveness of a sublingual, ergogenic spray on muscle strength and power. J Altern.Complement Med 2005;11(1):161-165. Progression despite replacement of a myopathic form of coenzyme Q10 defect. Barboni, P., Valentino, M. L., La, Morgia C., Carbonelli, M., Savini, G., De, Negri A., Simonelli, F., Sadun, F., Caporali, L., Maresca, A., Liguori, R., Baruzzi, A., Zeviani, M., and Carelli, V. Idebenone treatment in patients with OPA1-mutant dominant optic atrophy. Kim J, Medsinge A, Chauhan B, et al. Kogan, A. K., Syrkin, A. L., Drinitsina, S. V., and Kokanova, I. V. [The antioxidant protection of the heart by coenzyme Q10 in stable stenocardia of effort]. Iarussi, D., Auricchio, U., Agretto, A., Murano, A., Giuliano, M., Casale, F., Indolfi, P., and Iacono, A. Langsjoen, P. H., Folkers, K., Lyson, K., Muratsu, K., Lyson, T., and Langsjoen, P. Pronounced increase of survival of patients with cardiomyopathy when treated with coenzyme Q10 and conventional therapy. Proc Natl.Acad Sci U.S.A 3-1-1991;88(5):1646-1650. Wahlqvist ML, Wattanapenpaiboon N, Savige GS, and et al. A lung disease that makes it harder to breathe (chronic obstructive pulmonary disease or COPD). View abstract. Acta Neurol Belg. 2014;2014:798957. The dose of your warfarin (Coumadin) might need to be changed. 2011;(2):34-38. Coenzyme Q10 seems to decrease blood pressure. Liu Z, Tian Z, Zhao D, et al. Eur J Clin Nutr 2002;56:1137-42. Research Communications in Chemical Pathology and Pharmacology 1975;12(1):111-124. Safety and side effects View abstract. View abstract. J Sports Med Phys.Fitness 2011;51(2):305-312. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. It helps provide energy to cells. View abstract. View abstract. View abstract. The effect of coenzyme Q10 on idiopathic chronic dilated cardiomyopathy in children. J Investig Med. Alehagen U, Alexander J, Aaseth J. Supplementation with selenium and coenzyme Q10 reduces cardiovascular mortality in elderly with low selenium status. Leuk.Res 2007;31(1):19-26. 2016;53(Pt 2):265-73. Palacka, P., Kucharska, J., Murin, J., Dostalova, K., Okkelova, A., Cizova, M., Waczulikova, I., Moricova, S., and Gvozdjakova, A. Complementary therapy in diabetic patients with chronic complications: a pilot study. Nutrition 2009;25(3):295-302. First Conference of the International Coenzyme Q10 Association 2002; Gvozdjakova A, Kucharska J, Lepies P, and et al. View abstract. Effect of coenzyme Q(1)(0) supplementation on heart failure: a meta-analysis. Fernández-Vega B, Nicieza J, Álvarez-Barrios A, et al. Acta Otolaryngol. 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An open-labeled parallel arm interventional study was conducted in the cardiology unit of Hayatabad Medical Complex Hospital, Peshawar, Pakistan, from March 2020 to March 2021. Coenzyme Q10 and periodontal treatment: is there any beneficial effect? All rights reserved. Antioxid.Redox.Signal. Research shows that taking coenzyme Q10 does not improve liver function in people with hepatitis C who are not responding to conventional treatment. Gul, I., Gokbel, H., Belviranli, M., Okudan, N., Buyukbas, S., and Basarali, K. Oxidative stress and antioxidant defense in plasma after repeated bouts of supramaximal exercise: the effect of coenzyme Q10. Ugeskr Laeger 1998;160:3226-7. US Pharm 2000;25:28-41. Mov Disord 1996;11:321-3. Select a condition to view a list of vitamins. Turunen M, Olsson J, Dallner G. Metabolism and function of coenzyme Q. Biochim Biophys Acta 2004;1660:171-99. Expert.Opin.Pharmacother. View abstract. Early research suggests that taking coenzyme Q10 by mouth might prevent the progression of a rare form of diabetes that is inherited from the mother. 2010;93(1):272-275. 1994;107(1):242-247. Eur.J Neurol. Mol Aspects Med 1997;18:S159-68. Reduction of chemotoxicity and enhancement of antioxidant capacity of plasma in cancer patients treated with conventional therapy plus CoQ10. View abstract. However, be sure to take this supplement under your doctor's supervision. Endocr Pract 2003;9:417-70. Hearing loss. View abstract. J Am Osteopath.Assoc. A controlled study of 2 doses of idebenone in the treatment of Alzheimer's disease. View abstract. Pharmacotherapy 2001;21:797-806. Singh, R. B., Kartikey, K., Charu, A. S., Niaz, M. A., and Schaffer, S. Effect of taurine and coenzyme Q10 in patients with acute myocardial infarction. Tsuyama, Y., Adachi-Usami, E., and Takeda, N. A case of Kearns-Shy syndrome with later onset. Int J Sport Nutr 1997;7:197-206. View abstract. Arch Neurol 2007;64:938-44. case series with 5 patients. Sivitz, W. I. and Yorek, M. A. Mitochondrial dysfunction in diabetes: from molecular mechanisms to functional significance and therapeutic opportunities. Biofactors 1999;9(2-4):231-240. Breast cancer. Eur J Ophthalmol. View abstract. View abstract. Horvath, R., Schneiderat, P., Schoser, B. G., Gempel, K., Neuen-Jacob, E., Ploger, H., Muller-Hocker, J., Pongratz, D. E., Naini, A., DiMauro, S., and Lochmuller, H. Coenzyme Q10 deficiency and isolated myopathy. Mol Aspects Med 1997;18:S137-44. Mizuno, M., Quistorff, B., Theorell, H., Theorell, M., and Chance, B. 2008;48(4-6):191-201. Invest New Drugs 2001;19:81-3. Muscle pain caused by statin drugs (statin-induced myalgia). Snider, I. P., Bazzarre, T. L., Murdoch, S. D., and Goldfarb, A. Yang, X., Yang, Y., Li, G., Wang, J., and Yang, E. S. Coenzyme Q10 attenuates beta-amyloid pathology in the aged transgenic mice with Alzheimer presenilin 1 mutation. View abstract. Lockwood K, Moesgaard S, Yamamoto T, Folkers K. Progress on therapy of breast cancer with vitamin Q10 and the regression of metastases. J Endocrinol.Invest 2011;34(8):e224-e228. [Ptosis and asthenia manifesting a mitochondrial myopathy]. Folkers, K., Morita, M., and McRee, J., Jr. Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. View abstract. Mol.Aspects Med 1997;18 Suppl:S153-S158. View abstract. Antidepressant effects of open label treatment with coenzyme Q10 in geriatric bipolar depression.J Clin Psychopharmacol. Cordero, M. D., de, Miguel M., Moreno Fernandez, A. M., Carmona Lopez, I. M., Garrido, Maraver J., Cotan, D., Gomez, Izquierdo L., Bonal, P., Campa, F., Bullon, P., Navas, P., and Sanchez Alcazar, J. View abstract. Comparison of L-carnitine vs. Coq10 and vitamin E for idiopathic male infertility: a randomized controlled trial. Alehagen U, Aaseth J, Alexander J, Brismar K, Larsson A. Selenium and Coenzyme Q10 Supplementation Improves Renal Function in Elderly Deficient in Selenium: Observational Results and Results from a Subgroup Analysis of a Prospective Randomised Double-Blind Placebo-Controlled Trial. 2020;12(3):723. Comparison with a standard therapy]. View abstract. 7-15-2008;23(9):1223-1227. Liu, J., Wang, L., Zhan, S. Y., and Xia, Y. Coenzyme Q10 for Parkinson's disease. Zhonghua Shi Yan.He.Lin.Chuang.Bing.Du Xue.Za Zhi. Results from the Q-SYMBIO study. Artuch, R., Brea-Calvo, G., Briones, P., Aracil, A., Galvan, M., Espinos, C., Corral, J., Volpini, V., Ribes, A., Andreu, A. L., Palau, F., Sanchez-Alcazar, J. J Inherit.Metab Dis 2008;31(5):643-657. Evidence-based therapies are often limited by tolerability, hypotension, electrolyte disturbances, and renal dysfunction. The prevalence of ED in long-term hypertension (>5 years) can be explained by the high levels of angiotensin II in these patients. Taking coenzyme Q10 by mouth does not seem to improve symptoms in people with Parkinson disease. Ylikoski, T., Piirainen, J., Hanninen, O., and Penttinen, J. Chew, G. T., Watts, G. F., Davis, T. M., Stuckey, B. G., Beilin, L. J., Thompson, P. L., Burke, V., and Currie, P. J. Hemodynamic effects of fenofibrate and coenzyme Q10 in type 2 diabetic subjects with left ventricular diastolic dysfunction. Efficacy and safety of coenzyme Q10 supplementation in the treatment of polycystic ovary syndrome: a systematic review and meta-analysis. View abstract. Rusciani, L., Proietti, I., Rusciani, A., Paradisi, A., Sbordoni, G., Alfano, C., Panunzi, S., De Gaetano, A., and Lippa, S. Low plasma coenzyme Q10 levels as an independent prognostic factor for melanoma progression. A single blind placebo-controlled and randomized clinical study [abstract]. Int J Sports Med 1999;20(3):154-158. View abstract. Biochem Biophys Res Commun 1995;212:172-7. Clin Investig. It aids mitochondria during energy production and is a part of the endogenous antioxidant system. Henchcliffe, C. and Beal, M. F. Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis. Vitetta, L., Sali, A., and Reavley, N. J. There were no significant differences in demographics, history of illness, co-morbid conditions, and current medication of both groups. J Med Assoc Thai. View abstract. B., Delport, R., Vermaak, W. J., and Human, J. Amsterdam: Elsevier Science;1986. View abstract. View abstract. View abstract. View abstract. Am J Cardiol. Lancet 2000;356:391-5. View abstract. 2002;3(1-2):37-40. View abstract. Ju et al. Menke, T., Niklowitz, P., Wiesel, T., and Andler, W. Antioxidant level and redox status of coenzyme Q10 in the plasma and blood cells of children with diabetes mellitus type 1. View abstract. We commend Hansen and colleagues1 for reporting the randomized, double-blind, crossover trial which investigated the use of high-dose coenzyme Q10 (CoQ10) in patients with post COVID-19 condition (PCC). J Child Neurol. described that patients with concomitant ED and hypertension had a higher risk of cardiovascular issues [10]. Blood Press Suppl 1996;3:53-5. Is coenzyme Q10 helpful for patients with idiopathic cardiomyopathy? Taking coenzyme Q10 by mouth, alone or with other ingredients, doesn't improve athletic performance in athletes or non-athletes. Mortensen SA, Rosenfeldt F, Kumar A, Dolliner P, Filipiak KJ, Pella D,et al; Q-SYMBIO Study Investigators. View abstract. International Journal of Andrology 2000;Suppl 23:43. Mol.Aspects Med 1994;15 Suppl:s165-s175. Mol Aspects Med 1997;18 Suppl:S213-9. In a study conducted on men with Peyronie's disease, supplementation with 300mg of CoQ10 daily showed improvement in ED [12]. J Evid Based Dent Pract. South Med J 2001;94:1112-7. The most prevalent comorbidity among ED patients is hypertension, and more than half of the hypertensive males present with ED as a complication of hypertension [17]. Clin Cardiol. Acta Otolaryngol. Nat.Clin Pract Neurol. Satta, A., Grandi, M., Landoni, C. V., Migliori, G. B., Spanevello, A., Vocaturo, G., and Neri, M. Effects of ubidecarenone in an exercise training program for patients with chronic obstructive pulmonary diseases. 2015 Feb;238(2):329-35. doi: 10.1016/j.atherosclerosis.2014.12.016. View abstract. Eur.J Med.Res 11-12-2003;8(11):485-491. View abstract. 2012;259(2):284-291. Brain Dev. Free Radic.Res 2008;42(3):221-225. Cyrus-Hajmassy, M. [Bilateral visual deterioration in excessive tobacco and alcohol consumption]. 2005;62(4):621-626. Gokbel, H., Gul, I., Belviranl, M., and Okudan, N. The effects of coenzyme Q10 supplementation on performance during repeated bouts of supramaximal exercise in sedentary men. CoQ10 has antioxidant properties and protects against oxidative damages occurring in the body. Oda, T. Recovery of load-induced left ventricular diastolic dysfunction by coenzyme Q10: echocardiographic study. Sobreira C, Hirano M, Shanske S, et al. Folkers K, Simonsen R. Two successful double-blind trials with coenzyme Q10 (vitamin Q10) on muscular dystrophies and neurogenic atrophies. 2009;11(3):439-448. Effects of coenzyme Q10 on health-related quality of life, clinical disease activity and blood pressure in patients with mild to moderate ulcerative colitis: a randomized clinical trial. View abstract. Consent was obtained or waived by all participants in this study. Crane FL. 2. Belcaro, G., Cesarone, M. R., Dugall, M., Hosoi, M., Ippolito, E., Bavera, P., and Grossi, M. G. Investigation of Pycnogenol(R) in combination with coenzymeQ10 in heart failure patients (NYHA II/III). The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure. Pediatr Diabetes 2008;9(6):540-545. Effect of an antioxidant-rich multivitamin supplement in cystic fibrosis. View abstract. View abstract. Clin Ther. Int J Tissue React 1990;12:183-6. Desnuelle, C., Pellissier, J. F., Serratrice, G., Pouget, J., and Turnbull, D. M. [Kearns-Sayre syndrome: mitochondrial encephalomyopathy caused by deficiency of the respiratory chain]. Brain tissue biopsy findings and clinical course following pharmacological]. Folkers K, Hanioka T, Xia LJ, et al. London: Taylor and Francis;1990. View abstract. VI. Obesity. View abstract. Mol Cell Biochem 2003;246:75-82. Reducing exercise-induced muscular injury in kendo athletes with supplementation of coenzyme Q10. J Hum Hypertens 1999;13:203-8. Beyer RE, Nordenbrand K, and Ernster L. The function of coenzyme Q in free radical production and as an antioxidant: a review. Roland, L., Gagne, A., Belanger, M. C., Boutet, M., Berthiaume, L., Fraser, W. D., Julien, P., and Bilodeau, J. F. Existence of compensatory defense mechanisms against oxidative stress and hypertension in preeclampsia. View abstract. Kaikkonen, J., Kosonen, L., Nyyssonen, K., Porkkala-Sarataho, E., Salonen, R., Korpela, H., and Salonen, J. T. Effect of combined coenzyme Q10 and d-alpha-tocopheryl acetate supplementation on exercise-induced lipid peroxidation and muscular damage: a placebo-controlled double-blind study in marathon runners. [Clinical study of Wenxikeli treatment of viral myocarditis]. WebMD does not provide medical advice, diagnosis or treatment. View abstract. Adv Neurol 1988;48:239-256. 2018 Apr 11;13(4):e0193120. An in vivo study on brain and skeletal muscle by phosphorous magnetic resonance spectroscopy. Effect of coenzyme Q10 on essential hypertension: a double-blind controlled study. Schiapparelli, P., Allais, G., Castagnoli, Gabellari, I, Rolando, S., Terzi, M. G., and Benedetto, C. Non-pharmacological approach to migraine prophylaxis: part II. Mov Disord. Wyss V, Lubich T Ganzit GP Cesaretti D Fiorella PL Dei C Rocini C Bargossi AM Battistoni R Lippi A Grossi G Sprovieri G Battino M. Remarks on prolonged ubiquinone administration in physical exercise. View abstract. J Altern.Complement Med 2010;16(3):323-325. Sangouni AA, Taghdir M, Mirahmadi J, Sepandi M, Parastouei K. Effects of curcumin and/or coenzyme Q10 supplementation on metabolic control in subjects with metabolic syndrome: a randomized clinical trial. , this is the first study that investigates the role of CoQ10 showed! Sclerosis or ALS ) function of coenzyme Q10 is present naturally in the body A. dysfunction! Coq10 in ED [ 12 ] information may not fit your specific health circumstances muscle weakness and fatigue affect! Effect of coenzyme Q ( 1 ):32-42 be 58.3 % in hypertensive patients https: //www.fda.gov/orphan/DESIGNAT/list.htm Accessed... Amyotroph.Lateral.Scler.Other Motor Neuron Disord 2000 ; 132:636-40 G, Baskaran K, Simonsen R. Two successful trials... 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